- Boy Scouts of America
- Knights of Columbus
- Men's Club
- Hospitality Ministers
- Women's Club
- Widow's Club
- The Star (church newsletter)
- Crisis Ministries
- East Cooper Community Outreach (ECCO)
- Neighborhood House (soup kitchen)
- Community Service Committe
- Altar and Church Care
- Archives
- Bell Change Ringing
- Building and Grounds
- Choir
- Hospitality and Host Families
- Lectors
- Ushers
- Festival by the Sea Committee
- Weed, Feed and Seed
- Bereavement
- Ministry of Sick
- St. Vincent dePaul Society
- Miraculous Medal Novena and Benediction
- Marriage Encounter
- Nocturnal Adoration
- Christian Formation Classes
- Adult Catholic Awareness;
Rite of Christian Initiation of Adults (RCIA)
- Nursery
- Christian Formation Teachers
- Servants of Jesus Charismatic Prayer Group
- High School Youth Group
- Jr. High Youth Group
- High School Leadership Team
- Adult Discipleship Program
- Scripture Study: Catholic Perspectives
- M.O.M.S.: "Ministry of Moms Sharing"
- Vacation Bible School